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Aurélie BOUZELMAT

PARIS

En résumé

Experimentée dans une large variété de techniques de biologie moléculaire et épigénétique (extraction ADNn, PCR, PCR methyl-sensible, High Resolution Melting analysis, pyrosequencing, in-vitro methylation, Whole Genome Amplification, qPCR), et d'outils de bio-informatique (BLAST, Biology Workbench.

Entreprises

  • Hôpital Robert Debré - AP-HP - Éudiant

    maintenant Dans le laboratoire de diagnostisque de génétique moléculaire de l'hôpital Robert Debré. Paris.


    I developed a Methyl-Sensitive PCR of the human 14q32 intergenic differentially methylated region. My mission was to create a diagnosis method to identify epigenetic dysregulations leading to a Prader-Willi like syndrome. The technique was validated and is now available for the laboratory.

  • McGill Université - Étudiant

    2010 - maintenant Dans le laboratoire du Prof. Moshe Szyf, Departement de Pharmacologie Therapeutiques de la Faculté de Médicine, McGill Université. Montréal (Canada):

    Set up a pool of epigenetic biomarkers for liver cancer. I analyzed patients’ tumour and normal samples with HRM (High Resolution Melting analysis) in order to identify precise probes differentially methylated in cancer and normal samples. This pool could be used as an early diagnostic. I validated my results with pyrosequencing and built controls with Whole Genome Amplification (WGA) and in-vitro methylation.
    Patent on the process of being filed.

Formations

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