Damien MEYER

Bacterial pathogens and symbionts exploit a wide array of strategies to facilitate interaction with hosts. For endosymbiotic or intracellular pathogenic bacteria, there is a constant need to manipulate signaling pathways in the eukaryotic mammalian or arthropod host cell. I am particularly interested in the pathways used by intracellular pathogenic Ehrlichia bacteria to enter host cells and create a safe replicating niche. I am also investigating how endosymbiotic Wolbachia bacteria interact with eukaryotic cells. My research encompasses the underlying molecular mechanisms of these processes and the illumination of how these strategies facilitate unique interactions with the host immune system, most notably for immune evasion.
To this aim, I use a systems biology approach that goes from molecular and cellular biology to translational studies with particular emphasis on the interface between the bacterium and its host (vertebrate and invertebrate ; unicellular or multicellular). The unifying theme is the integrated study of infectious strategies of Anaplasmataceae (pathogenic Ehrlichia and symbiotic Wolbachia) in conjunction and communication with each other, their host, and the cellular environment they inhabit.
Findings from this work contribute to understanding the mechanisms of pathogenesis and endosymbiosis as well as advancement of human and animal health interests.

http://www.damienmeyer.fr

I am also a guitarist of the noisy pop rock band based in Guadeloupe and named PENNY DREADFULS. Check out our web page and listen to our single on itunes, deezer, spotify etc

http://pennydreadfuls.fr

Mes compétences :
Génomique
Microbiologie
Recherche
Transcriptomique
Bio-informatique
Biologie moléculaire