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Marie MATTERA

Toulouse

En résumé

After 10 years in the R&D in the pharmaceutical industry, I wanted to add more human relations to my work andbe closer to the patients.
I have completed my master's degree with a CRA mission in the Sponsor Team at Institut Claudius Regaud in Toulouse.
Dynamic, rigorous and team player, my main motivation is to improve health and quality of life of the patients.

Mes compétences :
Project Management
Monitoring
Oncology
ICH - GCP

Entreprises

  • CHU Toulouse - CRA

    Toulouse 2018 - maintenant Nephrology and Organ Transplantation team

  • Institut Claudius Regaud - Clinical Research Associate (Sponsor Team)

    2017 - 2017 Sponsor Team at Institut Claudius Regaud
    Oncology Studies
    Phases I to III, Pivotal studies and Other than health products studies

    Missions:
    • Monitoring
    • Site initiation and Site closure visits (reparation, visits and reports)
    • Study follow-up (calls with invesigators, sites CRA, gestion of internal data bases)
    • Detection of non-compliant situations and contact of the sites to define corrective actions
    • Contribution to patients samples collection from the investigation centers for the delivery to the analysis center
    • Management of Trial Master Files
    • Realization of Investigators and Pharmacy Site Files
    • Review of Data entry guide and eCRF training for Investigators and CRA
    • Management of the Serious Adverse Events (SAE) in collaboration with CRPV (Centre Régional de PharmacoVigilance : local pharmacovigilance center)
    • Writing of Newsletter and distribution to the centers
    • Archiving study documentation and correspondence

  • Sanofi - Research Scientist

    Paris 2006 - 2016 2012-Today : Oncology (Biologics Unit)

    Targets identification and validation
    Analysis of therapeutic antibodies activity
    Cell lines characterization (siRNA, Western Blot, FACS)
    PBMC purification
    ADCC assays

    2010-2012 : Exploratory Unit
    tudy of the mecanism of action of a family of Nuclear Receptors
    - Immunocytochemistry - Western Blot
    - Functionnal assays (reporter gene)
    - Site-directed mutagenesis
    - Generation of cell lines over expressing the nuclear receptors with lentivirus transduction

    2006-2010 : Central Nervous System
    Set up of several screening assays
    Cell culture
    Neurons and astrocytes primary culture
    MTS and LTS Screening : radioligand binding, gene reporter assays, calcium assays

  • Sanofi - Trainee

    Paris 2005 - 2006 Development of cell lines stably expressing a family of G-PCR
    - Cell culture
    - TA cloning
    - Plasmid purification
    - Generation of stable cell lines
    - Radioligands binding, HTRF assays

Formations

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