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Mei-Shiue KUO

NANTERRE

En résumé

With more than 10 years’ experience in biological research, especially in oncology, I want to continue this exciting work using bioinformatic approaches. To achieve this goal, I began to learn programming languages and bioinformatic tools for genomic data analysis since last March. I am currently pursuing a Master 2 degree in bioinformatics and looking for an internship of 6 months, ideally in cancer research, to give a substantial contribution and to enhance my skills in bioinformatics.

Certificates :
Statistics for Genomic Data Science by Johns Hopkins University on Coursera
https://www.coursera.org/account/accomplishments/verify/HET26L9K97PZ

Genomic Data Science with Galaxy by Johns Hopkins University on Coursera
https://www.coursera.org/account/accomplishments/certificate/77N4LEUR5FYL

Command Line Tools for Genomic Data Science by Johns Hopkins University on Coursera
https://www.coursera.org/account/accomplishments/certificate/R4RJ3LESDTXW

Algorithms for DNA Sequencing by Johns Hopkins University on Coursera
https://www.coursera.org/account/accomplishments/certificate/ZCWCEKL65SQJ

Python for Genomic Data Science by Johns Hopkins University on Coursera
https://www.coursera.org/account/accomplishments/certificate/Q8KZDWPEJBPL

Mes compétences :
Bioinformatic : Unix/ Linux, Python, R + Bioconduc
Purification of recombinant proteins
Biochemistry: Western blot, immunofluorescence, EL
Cellular biology: development of ex vivo cell mode
Molecular biology: DNA and RNA extraction, RT-PCR,

Entreprises

  • Bioinformatics platform at Gustave Roussy - Internship

    2018 - 2018 Comparison of copy number (CGH) profiles to validate the methods used by different platforms

  • Gustave Roussy Cancer Centre - Research Scientist at

    Villejuif 2013 - 2017 Project manager in generation of heterodimer-specific antibodies
    - Strategy conception of antibody production and methodology development
    - Setup of high throughput assays for antibody selection and of analytical assays for antibody characterization

  • Saint-Louis Hospital ((Inserm U940) - Post-doctoral Scientist

    2012 - 2013 Setting up melanoma histocultures for anti-cancer drug discovery

  • Cochin Institute - Post-doctoral scientist

    2011 - 2012 Development of BRET-based assays for small molecules screening : treatments for diabetes

  • University Institute for Haematology - Post-doctoral scientist

    2010 - 2010 Two parallel projects :
    (1) study of the role of a co-chaperone protein in the protein secretion : application for recombinant proteins production
    (2) evaluation of anticancer activity of therapeutic inhibitors : application for cancer treatments

    - methods design, experiments execution for proteins purification and interacting proteins identification
    - establishment of collaborations
    - supervision of a undergraduate student (2 months)

  • Cochin Institute - PhD student (3 and half years) + Post-doctoral scientist (3 months)

    2005 - 2009 Study of the role of O-GlcNAcylation of FoxO1 in the regulation of hepatic glucose production
    - identifying proteins with different O-GlcNAcylation levels by 2D-DIGE (diabetic vs. control mice)
    - developing techniques for enzyme and protein assay (proteins and protein-DNA interactions, experiments design and execution
    - analysis, drafting and presentation of results
    - training of new staff members

  • Study of the role of glucotoxicity in the regulation of hepatic glucose production - Engineer Internship

    2004 - 2005 Production of proteins involved in the radiation-resistance of Deinococcus radiodurans
    - optimization of processes in purification and production of targeted proteins for crystallographic studies
    - monthly report writing and meetings with customers (in English)

  • National Congress of Taiwan - Parliamentary assistant

    2002 - 2003 - information collecting, reviewing and providing feedback of the acts related to public health, environment, informatics, technologies and sciences
    - organization of consultative meetings in the field of public health and health insurance

  • Taïwan BioTech Association (Taipei, Taïwan)

    2001 - 2002

Formations

Réseau

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