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Nicolas BABAULT

NEW YORK

En résumé

• Energetic, enthusiastic and passionate scientist with extensive knowledge and experience in Structural Biology/Biochemistry. Expertise from gene to structure using a Structure Based Drug Design approach. Responsibilities have spanned Protein expression/purification, Characterization of Small molecule/Protein Interaction using biophysical methods (ITC, SPR, DSF) and biochemical assays, Structures determination…

• Served as research scientist for four research labs. Most recently, developed and lead a structural biology group in a chemistry lab as an effort to expand the lab expertise and increase collaborations.

• Well organized, motivated and driven personality. Collaborative in interpersonal style with experience working with cross-functional teams.

Mes compétences :
Project Management
Project planning
Team Management
Social Skills
Structural Biology
Mentoring Experience
Biochemistry
Lab management
Drug Discovery

Entreprises

  • Icahn School of Medicine at Mount Sinai - Group Leader

    2014 - maintenant Jian Jin lab
    Department of Pharmacological Sciences. Icahn School of Medicine at Mount Sinai.
    New York, United States.
    ``Structure Based Drug Design of Methyltransferase inhibitors''
    Structural/Biophysical characterization of protein/small molecule inhibitor complexes

  • Mount Sinai School of Medicine - Postdoctoral fellow

    2012 - 2014 Ming-Ming Zhou lab
    Department of Structural and Chemical Biology. Mount Sinai School of Medicine.
    New York, United States.
    ``Structural studies of proteins involved in epigenetic mechanisms''
    Structural/Biochemical characterization of protein/ligand complexes.

  • Columbia University - Postdoctoral fellow

    2011 - 2012 Alexander Sobolevsky lab
    Department of Biochemistry & Molecular Biophysics. Columbia University. New York, United States.
    ``Studies of ion channel structure using biophysical and biochemical approaches''
    Cloning; Expression/Purification of membrane proteins from insect cells.

  • Institut Pasteur - PhD student

    Paris 2007 - 2011 Unit of NMR of biomolecule, Institut Pasteur. Paris, France
    ``Structural studies of the human Tyrosine Phosphatase PTPN4, a target to trigger
    neuronal death''
    Expression/Purification and biophysical characterization of protein/ligand complexes.

  • Institut de Biologie Physioc-Chimique - Research Scientist

    2006 - 2007 Laboratory of Physical and Chemical Biology of Membrane Proteins, IBPC. Paris,
    France
    ``Biophysical study of the chlorophyll a of the cytochrome b6f complex from
    Chlamydomonas reinhardtii''
    Expression/Purification and biophysical characterization of membrane protein.

Formations

  • University Of Paris VI

    Paris 2007 - 2011 Doctor of Philosophy

    Ph.D., Structure, Function and Protein Engineering.

  • University Of Paris VII

    Paris 2005 - 2007 Master of Science

    Biochemistry

    One-year exchange program at Concordia University, Montreal, Canada (2005)

Réseau

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