Mes compétences :
Humain skin research
Materials science
International Management
Client Management
Communication
Technical Support
Sales development
Entreprises
NOVITOM
- R&D and Sales Engineer in Pharma-Cosmetics, Materials
2018 - maintenant- Commercial development with the sectors: cosmetics, pharmaceuticals, plastic composites, elastomers.
- The sale of our "high-range / unconventional" scientific expertise to the R&D and/or marketing departments.
- Analyze and understand new trends / techniques from different markets internationally
- Understand and analyze needs, strategies and expectations of customers, give the appropriate solutions, vulgarization of our techniques
- Establish quotes, followed from A to Z of each project, piloting multilateral projects
- Participation of exhibitions with or without company booths, research of marketing tendency, build a network, propose visits ...
Novitom is an independent company, specialized in 3D material characterisation, NDT and microanalysis based on advanced imaging techniques including synchrotron technology : X Ray Tomography, X Ray Microdiffraction, SEM-FEG Microscopy, X Ray Microscopy Flouorescence, FTIR, etc.
Fields of activities: pharmaceuticals and cosmetics, agri-food, plastic composites and elastomers ...
We are looking forward to working with you such as feasibility study, in vitro study and clinical study
website: http://www.novitom.com
Pierre Fabre
- R&D
Castres2013 - 2017Skin aging and cumulative exposure to UVs within a lifetime affects a number of actors in the extracellular matrix such as collagen, elastin, glycans and associated biomolecules (metalloproteinases and their inhibitors, hyaluronidases, etc). The concentration, structure and / or distribution, and the hydric organization are modified by this phenomenon. All these modifications result in a loss of function of the matrix and the clinical manifestations of aging.
The aim of this thesis, carried out in collaboration with the Skin Research Center of Pierre Fabre Dermo-Cosmétique, is to analyze the changes in the dermis and the hydric organization within the matrix with age and under the effect of UVs to help the knowledge of skin alteration under these conditions. Given the different scales to be explored - from Angstrom to the micron - a combination of different techniques is necessary to reach the macromolecular dynamics via behavior laws.
Firstly, we validated the use of infrared spectroscopy (FTIR), differential scanning calorimetry (DSC) and thermostimulated Currents (TSC) techniques to analyze human cutaneous biopsies. These techniques were proven to be suitable to scan the dermis over a wide range of scales and to provide relevant information on the main macromolecules of the dermis and the different water structures.
Then we studied the evolution of thermal, dielectric and vibrational signatures of the dermis during chronological aging and photo-aging via a clinical study involving subjects from two age groups (20-30 years and over 60 years). Markers of intrinsic and extrinsic aging have been extracted from this work.
The evolution of these signatures was also studied in an ex vivo study on the effects of UV exposure of dermis, leading to a better understanding of the different mechanisms involved in chronological aging and photo-aging.
