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UMRS1135_CIMI_"Immunity and infection",Faculté de Médecine Pitié-Salpêtrière
- CHERCHEUR
2012 - maintenant
Identification des gènes impliqués dans l’évolution des maladies virales chroniques et en particulier les infections par le VIH-1 et l’hépatite C.
Publications:
Uttayamakul S, Oudot-Mellakh T, Nakayama EE, Tengtrakulcharoen P, Guergnon J, Delfraissy JF, Khusmith S, Sangsajja C, Likanonsakul S, Theodorou I, Shioda T. Genome-wide association study of HIV-related lipoatrophy in Thai patients: Association of a DLGAP1 polymorphism with fat loss. AIDS Res Hum Retroviruses. 2015 May 7.
Bouthemy C, Nel I, Oudot Mellakh T, Theodorou I. Host's genetics in HIV disease. Pathol Biol (Paris). 2013 Jan;61(1):17-20.
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UMR_S 937_ Cardiovascular Genomics, Faculté de Médecine Pitié-Salpêtrière
- Post-doc
2010 - 2011
Genetic Determinants of Quantitative Traits in Thrombotic Disease
Publications:
Morange PE, Oudot-Mellakh T, Cohen W, Germain M, Saut N, Antoni G, Alessi MC, Bertrand M, Dupuy AM, Letenneur L, Lathrop M, Lopez LM, Lambert JC, Emmerich J, Amouyel P and Trégouët DA. KNG1 Ile581Thr and susceptibility to venous thrombosis. Blood. 2011 Mar 31;117(13):3692-4. Epub 2011 Jan 26.
Antoni G, Oudot-Mellakh T, Dimitromanolakis A, Germain M, Cohen W, Wells P, Lathrop M, Gagnon F, Morange PE, Tregouet DA. Combined analysis of three genome-wide association studies on vWF and FVIII plasma levels. BMC Med Genet. 2011 Aug 2;12:102.
Oudot-Mellakh T, Cohen W, Germain M, Saut N, Kallel C, Zelenika D, Lathrop M, Trégouët DA, Morange PE. Genome wide association study for plasma levels of natural anticoagulant inhibitors and protein C anticoagulant pathway: the MARTHA project. Br J Haematol.2012 Apr;157(2):230-9.
Germain M et al., Genetics of venous thrombosis: insights from a new genome wide association study. PLoS One. 2011;6(9):e25581.
Germain M, Saut N, Oudot-Mellakh T, Letenneur L, Dupuy AM, Bertrand M, Alessi MC, Lambert JC, Zelenika D, Emmerich J, Tiret L, Cambien F, Lathrop M, Amouyel P, Morange PE, Trégouët DA. Caution in interpreting results from imputation analysis when linkage disequilibrium extends over a large distance: a case study on venous thrombosis. PLoS One. 2012;7(6):e38538.
Tang W et al., Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease. Am J Hum Genet. 2012 Jul 13;91(1):152-62.
Huang J et al., Genome-wide association study for circulating levels of PAI-1 provides novel insights into its regulation. Blood. 2012 Dec 6;120(24):4873-81.
Sabater-Lleal M et al., Multiethnic meta-analysis of genome-wide association studies in >100 000 subjects identifies 23 fibrinogen-associated Loci but no strong evidence of a causal association between circulating fibrinogen and cardiovascular disease. Circulation. 2013 Sep 17;128(12):1310-24.
Bonora E, Rizzato C, Diquigiovanni C, Oudot-Mellakh T, Campa D, Vargiolu M, Guedj M; The NMTC Consortium, McKay JD, Romeo G, Canzian F, Lesueur F. The FOXE1 locus is a major genetic determinant for familial nonmedullary thyroid carcinoma. Int J Cancer. 2014 May 1;134(9):2098-107. doi: 10.1002/ijc.28543. Epub 2013 Oct 31.
Huang J et al., Genome-wide association study for circulating tissue plasminogen activator levels and functional follow-up implicates endothelial STXBP5 and STX2. Arterioscler Thromb Vasc Biol. 2014 May;34(5):1093-101. doi: 10.1161/ATVBAHA.113.302088. Epub 2014 Feb 27.
Baumert J et al., No Evidence for Genome-Wide Interactions on Plasma Fibrinogen by Smoking, Alcohol Consumption and Body Mass Index: Results from Meta-Analyses of 80,607 Subjects. PLoS One. 2014 Dec 31;9(12):e111156. doi: 10.1371/journal.pone.0111156. eCollection 2014.
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CEA-Centre National de Génotypage (C.N.G), Evry, France.
- Doctorant
2005 - 2009
Thèse: "Recherche de gènes de prédisposition à une maladie à hérédité complexe: le psoriasis"
Publications:
Lesueur F, Lefèvre C, Has C, Guilloud-Bataille M, Oudot T, Mahé E, Lahfa M, Mansouri S, Mosharraf-Olmolk H, Sobel E, Simon Heath, Lathrop M, Dizier MH, Prud’homme JF, and Fischer J. Confirmation of psoriasis susceptibility loci on chromosome 6p21 and 20p13 in French families. Journal of Investigative Dermatology, 127:1403-1409, 2007
Lesueur F, Oudot T, Heath S, Foglio M, Lathrop M, Prud’homme JF, and Fischer J. ADAM33, a New Candidate for Psoriasis Susceptibility. PLoS One, vol.2, p.e906, 2007
Oudot T, Lesueur F, Guedj M, de Cid R, McGinn S, Heath S, Foglio M, Prum B, Lathrop M, Prud’homme JF, and Fischer J. An Association Study of 22 Candidate Genes in Psoriasis Families Reveals Shared Genetic Factors with Other Autoimmune and Skin Disorders. Journal of Investigative Dermatology, 2009 Jun 25
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CEA-C.N.G, Evry, France.
- Stage de DEA
2004 - 2004
Recherche de variations dans des gènes candidats dans la prédisposition au psoriasis
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CEA-C.N.G
- Stage de licence
2002 - 2002
Cartographie fine des loci candidats pour une maladie rare de la peau, l'ichtyose
