Yassine RECHOUM

En résumé

Entreprises

• Baylor College of Medicine - Instructeur

  2015 - maintenant

• Baylor College of Medicine - Postdoctoral Associate

  2010 - 2015 Translational Research in Oncology - Current projects:
  Project#1: Demystify the role of the Androgen Receptor in the resistance to aromatase inhibitors in ER-positive breast cancer
  
  Project#2: Identify molecular signature(s) for outcomes of triple negative breast cancer
  
  Project#3: Identify new targets in triple-negative breast cancer
  
  Accomplishments:
  
  * Engineered in vivo (mice) and in vitro (cell lines, primary & stable) preclinical models to investigate the effect of new and approved drugs ;
  * Performed mechanistic studies using gain- and loss-of-function approaches such as gene silencing and protein expression
  * Analyzed IHC slides for micrometastasis ;
  * Analyzed microarray data and queried datasets for prognosis value and gene signatures using statistical tools and software (R language)
  * Analyzed, interpreted, and reported experimental results internally as well as at international translational meetings
  * Collaborated with external labs and pharmaceutical companies to assess the effects of drug treatments in our preclinical models
  * Supervised students and participated in teaching ;
  * Used Quality Assurance tools and guidance to write protocols, trace and keep records ;
  * Troubleshot experiments

• Université Joseph Fourier - ATER

  Saint-Martin-d'Hères 2007 - 2009 * Prepared and executed lab sections and class lectures in fundamental microbiology, immunotechniques and genetic diseases
  

• HybrIsère - Research and Development Engineer

  2004 - 2005 * Extracted splenocytes from immunized mice and generated / maintained hybridomas
  * Generated monoclonal antibodies using ascites and bioreactors
  * Optimized cell culture conditions and increased efficiency of antibody production by over 50%

Formations

• Université Grenoble 1 Joseph Fourier

  Grenoble 2005 - 2009 Doctor of Philosophy

Réseau

• Michel SEVE