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Alice CHAN

PARIS

En résumé

Diplômée d'un Doctorat en Biochimie, Chimie & Sciences du Vivant, j'ai une formation pluridisciplinaire (Licence en Biotechnologies, Master en Biologie, formée en Biophysique, Management de projets & innovation, Marketing Industriel et Valorisation de la recherche). Très motivée et dynamique, je m'adapte rapidement à de nouvelles conditions et ceci grâce à une organisation et une gestion efficace du travail qui me permettent de bien gérer divers projets. Ayant une expérience scientifique et non scientifique variée, j'utilise une approche pluridisciplinaire et ouverte issue de mes connaissances et de mon expérience pour l'étude d'un sujet et la résolution de problèmes. Autonome et indépendante, je suis aussi de contact facile. Ayant de bonnes qualités relationnelles et de communication, j'aime aussi travailler en équipe ou en collaboration comme je l'ai souvent fait. L'intérêt que j'ai pour toutes les cultures et les voyages et mon amour des langues y sont pour beaucoup. Par conséquent, je recherche un poste où je pourrais mettre à profit mes connaissances et mes compétences. De par ma formation, mon expérience professionnelle et mes goûts pour la lecture, la traduction de textes et l'écriture, je suis à l'aise avec toute communication orale et écrite.

Graduated with a PhD in Biochemistry, Chemistry & Life Sciences, I have a multidisciplinary training (Bachelor in Biotechnology, Master in Biology, Biophysics & Chemistry, Project Management & Innovation, Marketing & Research Valorization courses). Highly motivated and dynamic, I adapt quickly to new conditions thanks to an effective organization and management of work which allow me to manage easily and successfully multiple projects. Having a wide scientific and non-scientific experience, I use an open-minded and multidisciplinary approach outcome of my knowledge and my experience to solve problems. Autonomous and independent, I have as well good communication & expression skills. I enjoy working in a team and with collaborators as I often did. It can be explained by the facts that I enjoy studying languages and that I'm interested in all cultures and in traveling. Therefore, I'm looking for a position where I can use my knowledge and my skills. Through my education, my work experience and my taste for reading, translating texts and writing, I'm very proficient with written & oral presentations.

Mes compétences :
Informatique
Encadrement de stages
langues étrangères
Accueil de groupes
Accueil des clients
Ecriture
Traduction anglais français
Enseignement universitaire
Gestion de projet
Microsoft Excel
Microsoft Word
Accompagnement
Accueil du public
Microsoft PowerPoint

Entreprises

  • Université de Grenoble - Teacher (Practical Work)

    2012 - 2012 Teaching (Practical work) Chemistry lessons (CHI110) & Cellular Biology lessons (BIO232) to undergraduate students at Grenoble University (Joseph Fourier University)
  • CEA-Grenoble (France) - Co-Encadrante de stages en Biochimie et Biologie

    PARIS 2012 - 2014 Encadrement de stages en Biochimie et Biologie (étudiants Licence, Master)
  • CEA-Grenoble (France) - Doctorante en thèse de Biochimie, phD student

    PARIS 2011 - 2014 Biochemistry thesis (UMR 5249, CEA/CRNS/UJF)
    Supervisor: S. OLLAGNIER de CHOUDENS, DR1
    Subject: Structure & mechanism of the Quinolinate Synthase, an enzyme with a [4Fe-4S]2+ cluster & a target of antibacterial agent
    Tools: Molecular Biology: Cloning, mutagenesis, PCR, informatics tools (sequence alignment, secondary structure prediction…)
    Cellular biology: In vivo tests
    Biochemistry: Purification & protein preparation (AKTA, BIORAD systems) & analysis (activity tests) in anaerobic conditions (Glovebox)
    Biophysics: UV-visible, HYSCORE, Mössbauer spectroscopies, circular dichroïsm
    Structural Biology: protein cristallogenesis, optimization of protein crystallization conditions, secondary structure prediction (ESPript) & structure visualization (PYMol)

    SCIENTIFIC PRODUCTIONS:

    Chan, A.; Clémancey, M.; Mouesca, J. M.; Amara, P.; Hamelin, O.; Latour, J. M.; Ollagnier de Choudens, S., Studies of inhibitor binding to the [4Fe-4S] cluster of quinolinate synthase. Angew Chem Int Ed Engl 2012, 51 (31), 7711-4.

    Cherrier, M. V.; Chan, A.; Darnault, C.; Reichmann, D.; Amara, P.; Ollagnier de Choudens, S.; Fontecilla-Camps, J. C., The crystal structure of Fe₄S₄ quinolinate synthase unravels an enzymatic dehydration mechanism that uses tyrosine and a hydrolase-type triad. J Am Chem Soc 2014, 136 (14), 5253-6.

    Poster presentation in:
    - French Group of BioInorganic Chemistry (FrenchBIC) in 2012 (alias Metalloprotein & models Club)
    - International Meeting in the Institute of Metals in Biology of Grenoble in 2013

    Oral presentation in:
    - International Meeting in the Institute of Metals in Biology of Grenoble in 2014
    - CEA “Young Researchers” Meeting in 2014
  • Université Paris-Sud - Biochemistry Intern

    Orsay 2011 - 2011 Biochemistry Internship (UPR 3082, LEBS Laboratory, South Paris University);
    Supervisors: M. ZEGHOUF, CR1 & J. CHERFILS, DR1
    Subject: Study of an exchange factor of Arf, BRAG2
    Tools: Protein purification (AKTA System), Fluorescence, membrane fractionation (flotation tests, PIP-STRIP), bioinformatics (Sequence alignment, secondary structure prediction)
  • UPMC - Biochemistry Intern

    Paris 2010 - 2010 Biochemistry Internship (UMR 8256, ERL INSERM U1164, UPMC University);
    Supervisor: C. EL AMRI, MCF
    Subject: In vitro Effects & characterization of nucleotides biosynthesis inhibitors
    Tools: Activity tests, DSC Calorimetry, Circular dichroïsm
  • UPMC - Biology Intern

    Paris 2010 - 2010 Biology Internship (UMRS 787, Myology Institute);
    Supervisors: A. FERREIRO, CR1 & S. ARBOGAST
    Subject: Selenoprotein N interactions
    Tools: Co-immunoprecipitation, Western blot, immunofluorescence, cellular fractionation
  • UPMC - Chemistry Intern

    Paris 2009 - 2009 Chemistry Internship (UMR 7203, UPMC University);
    Supervisor: P. KAROYAN, Professor
    Subject: Peptido-mimetics synthesis
    Tools: Synthesis, Thin-layer chromatography, flash chromatography.
  • Mairie de Paris - Caretaker of elementary schools

    Paris 2008 - 2013 Summers 2008 to 2013: Caretaker in elementary schools in 7th – 15th district of Paris
  • Temps Jeunes - Receptionist, facilitator & entertainer for children

    2008 - 2013 Summers 2008 to 2013:
    Receptionist, facilitator & entertainer for children, in Temps Jeunes Agency, in Paris 20e (welcoming family, taking care & entertaining children, organizing trip)
  • Château de Versailles - Receptionist

    Versailles 2007 - 2007 Receptionist in Versailles Castle (Marie-Antoinette Domain)
  • Monoprix - Sales person, cashier

    Clichy 2005 - 2006 Summers 2005 & 2006: Sales person & cashier in Monoprix Vaugirard, Paris 15e

Formations

  • Université Grenoble 1 Joseph Fourier

    Grenoble 2012 - 2013 Industrial Marketing & Marketing in R & D activity
  • Université Joseph Fourier Et INSTN (CEA)

    Grenoble 2011 - 2014 Doctorat en Biochimie, Chimie et Sciences du Vivant

    Chemistry & Living Sciences thesis in CEA Grenoble, in the Laboratory of Metals Chemistry & Biology, in Biocatalysis Team directed by Marc Fontecave
    Thesis supervisor: Sandrine Ollagnier de Choudens
    Subject : Structure & mechanism of the Quinolinate Synthase, an enzyme with a [4Fe-4S]2+ cluster & target of antibacterial agents
  • CEA (Paris)

    Paris 2011 - 2014 Project Management and R & D in Life Sciences
    Team Building, Technology Transfer, Intellectual Property & STI tools
    Valorization of Research & Innovation Management
  • Université Pierre Et Marie Curie Paris 6 (UPMC)

    Paris 2009 - 2011 Master degree in Biochemistry, Molecular & Cellular Biology

    Specialty : Biochemistry, Molecular & Cellular
    Genomics, pharmacology & physiopathology classes
  • UPMC

    Paris 2007 - 2009 Bachelor degree in Technology & Living Sciences

    Specialty : Living Sciences & Biotechnologies
    Chemistry, Biochemistry, Enzymology, Physiopathology classes...

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