Having been trained in Physics and Mathematics, I obtained a Master`s degree in Physics at the Univ of Dakar, Senegal. Then, in 1969, I joined the laboratory of Plant Biochemistry (CNRS/ Marseilles Univ; Pr J Ricard) to prepare a thesis on the physicochemical properties of various plant hemeproteins (stopped-flow; T-Jump relaxation and low temperature kinetics). I was recruited at CNRS in 1970. This work was extended during two postdoctoral fellowships at the Dept of Chemistry (Pr HB Dunford, Univ Alberta, Canada), then at the Univ of Newcastle upon Tyne, (Pr P Jones, UK).
In 1980, back to Marseilles, I started studying the mechanisms of transcription in plants. Major findings were the elucidation of the mechanisms contributing to the processivity of transcription elongation, the mechanism of action of α-amanitin and the influence of the sequence and conformation of the DNA template on the velocity and fidelity of transcription.
In 1992, I moved to Lyon to integrate the UMR041 CNRS/Rhône-Poulenc, a public-private joint laboratory, now the UMR5240 CNRS/Bayer CropScience (Pr R Douce), to work on seed physiology and on the characterization of plant specific metabolic pathways (essential amino acids and vitamins). I was successively deputy Head, then Head, then again deputy Head of this laboratory over the period 1993-2010. In 1999, I started a systematic study of the Arabidopsis seed proteome.
I have been, since 2000, involved in the promotion of plant genomics in France (Genoplante) and Europe (Plant KBBE). Also, since 2008, I have been working toward the establishment of an International Plant Proteomics Organization (INPPO), of which I was the first president.
I am member of the Editorial Board of Molecular & Cellular Proteomics, Seed Science Research, and Associate Editor of Frontiers in Plant Proteomics. I am Emeritus CNRS Research Director from 5 June 2012, consulting Professor at AgroParisTech and Member of the French Academy of Agriculture.
Mes compétences :
Physiology
Seeds
Plants
Genomics
Proteomics
Chimie
Pas de formation renseignée