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Edwige PICAZO

NEWCASTLE UPON TYNE

En résumé

Mes compétences :
LCMS
HPLC
Chimie analytique
RMN
Synthèse organique
Chromatographie
Chimie medicinale
Chimie organique
Chemical Synthesis
Solid-Phase Peptide Synthesis
Chromatography
Drug Discovery
FTIR
LC-MS
Laboratory supervision
NMR
Organisational Skills
Problem Solving
Project Management
Small Molecules
Teamwork
aided drug design
communication
good oral communication skills
industrial experience
macrocycle design
Microsoft Excel
Microsoft PowerPoint
Microsoft Word

Entreprises

  • Newcastle Institute for Cancer Research - PhD Student

    2015 - maintenant
  • Taros Chemicals GmbH - Scientist & Organic chemist in the Medicinal Chemistry department

    2013 - 2015 Library synthesis for the European Lead Factory (funded by the Innovative Medicines Initiative):
    - Library validation: Reaction conditions optimization to find a short, robust and scalable route for the synthesis of hundreds of target compounds
    - Library production: Multi-parallel synthesis from multi-gram scale to milligram scale, combinatorial chemistry with most diversification at last step of synthesis
    - Development of synthetic methodology leading to novel bis-spirocyclic-based compounds
  • Solvay - Stagiaire

    Paris 2013 - 2013 Développement et optimisation de synthèses de monomères (dérivés de méthyl méthacrylates), par transestérification.
  • Solvay S.A - Intern in the Synthesis and Process department

    2013 - 2013 Methodology project: Development and optimization of synthesis of methyl methacrylate derivatives by transesterification while keeping their ideal properties for coating applications
  • Novartis Pharma AG - Trainee in the Chemical Development department

    RUEIL MALMAISON 2012 - 2012 Green chemistry project: optimizing the synthesis of amides when changing solvents, solid-phase peptide synthesis with alternative solvents
  • Novartis - Stagiaire

    RUEIL MALMAISON 2012 - 2012 Optimisation de synthèses lors d'un changement de solvant (chimie verte)
    Synthèse de peptides en phase solide
  • F.Hoffmann-La Roche AG - Trainee

    2011 - 2011 Synthesis project:
    • Chemical synthesis of bi-aryl compounds mainly via Suzuki coupling
    • Intramolecular hetero Diels-Alder reaction via flow chemistry
  • Roche - Stagiaire

    Meylan 2011 - 2011 Synthèse d'une grande variété de nouveaux composés pharmaceutiques principalement par réaction de Suzuki et Sonogashira
    Purification de ces composés organiques par chromatographie
    Caractérisation par RMN et LCMS
  • Laboratoire de Chimie Organique et Therapeutique de Mulhouse - Stagiaire

    2011 - 2011 Synthèse de molécules nécessaires à la synthèse totale de mycolactones
    Purification par flash chromatographie
    Séchage de solvants

Formations

  • Newcastle University (Newcastle Upon Tyne)

    Newcastle Upon Tyne 2015 - maintenant Supervisor: Prof. Michael J. Waring

    Design and synthesis of chemical probes for PRMTs to act as tools for target validation and potential starting points for drug discovery.
    - Literature review of biological background and existing probes
    - Via computer-aided drug design, identification of targets of interests
    - Design, development and optimization of chemical routes to achieve targets
    - Structur
  • Université De Haute Alsace

    Mulhouse 2012 - 2013 Master


  • Ecole Nationale Supérieure De Chimie De Mulhouse ENSCMu (Mulhouse)

    Mulhouse 2009 - 2013 Diplome ingenieur chimiste
  • Centre International De Valbonne

    Sophia Antipolis 2007 - 2009 Classe preparatoires Physique-Chimie

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