PARIS 5
My laboratory, located in the "Institut Curie" in Paris (France), is devoted to the better understanding of pathophysiological consequences associated to chronic oxidative stress.
The discovery of free radicals -highly unstable molecules present at low levels in our body- have greatly modified our view of certain biological processes. Free radicals are constantly produced in the body, notably by metabolism and cellular respiration, but this physiological production is controlled by “antioxidant” defense systems. However, when an imbalance arises, either because of antioxidant deficiency or overproduction of radicals, the excess of these radicals becomes toxic and is called “oxidative stress”. Now, the toxic derivatives of oxygen (or ROS, reactive oxygen species) are implicated in numerous diseases, including cancer. If we can understand the mechanisms that lead to accumulation of ROS, we will be better equipped to fight against cancer.
Mes compétences :
Molecular and Cellular Biology
Pas de formation renseignée
