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Mariam SABBAR

CORBEIL ESSONNES

En résumé

I am a PhD, and I am looking for a Research assistant position, or a position in clinical and pharmaceutical companies.
I received my doctorate in April, 2013 in Neuroscience from the Mohammed V University -Rabat, Morocco.
My PhD focus into the study of "Lead toxicity consequences on basal ganglia activity and circadian rhythms in the rat: Electrophysiological, neurochemical and immunohistochemical approaches".
I have a great interest on research especially on Neurodegenerative disease and I would like to continue working in this exciting and wide ranging area.
My previous experiences are mainly on in vivo electrophysiology, behavioral tests like Open Field, rotarod, elevated plus maze; local injection of 6-OHDA on Subtantia nigra compacta. I also performed many histological techniques cryostat-cut, acetylcholine esterase, tyrosine hydroxylase staining and many other techniques.

Mes compétences :
HPLC
chirurgie animale
perfusion transcardiaque
Immunohistochimie
Electrophysiologie
Expérimentation animale

Entreprises

  • Institut de physiologie et de biochimie vétérinaire, Giessen, Allemagne - Chercheur postdoctoral

    2016 - 2016

  • University of the Witwatersrand, Faculty of Health Sciences - Chercheur postdoctoral

    2014 - 2016 Project1: The effects of an early-life infection, with different Streptococcus pneumoniae serotypes, on neurodevelopment and cognitive functioning in rats.

    Project2: Sickness responses following simulated ‘atypical’ central bacterial infection in rats.
    Project3: Investigating the temporal sequence of Nuclear Factor Interleukin-6 expression in the neonatal rat brain during pneumococcal cell wall-induced meningitis

  • Institut des maladies neurodégénératives - Doctorante stagiaire

    2010 - 2011 Cell biology skills

    HPLC: High-performance liquid chromatography
    Surgical procedures and neural activity assessment:
    Stereotaxic surgery on rats (brain lesion)
    In vivo electrophysiological recordings (extracellular, single-unit) in anesthetized rat.
    Intracardiac perfusion and Histology (brain slicing, Immunohistochemistry and Histological staining).

    Behavioral experiments

    Anxiety assessment: “elevated plus maze”,
    Motor assessment: “actimetry or Open Field”, “Rotarod”,
    Depression evaluation: “sucrose test”

    Signal processing
    Spike sorting and electrophysiological data processing (Neuroexplorer) in anesthetized
    rats.

  • Laboratoire Cognition Mouvement et adaptation - Doctorante stagiaire

    2008 - 2010 Stage de recherche comportement moteur et non moteur du rat et électrophysiologie

Formations

  • Institut Cellule Souche Et Cerveau, U846, Equipe: Neurobiologie Des Rythmes Circadiens Et Du Sommeil

    Bron 2011 - 2011 Doctorante Stagiare

    Behavioral experiments
    Circadian locomotor activity recording “CAMS system”

    Signal processing
    Clocklab for analyzing actogramm in CAMS

  • Université Mohammed V Agdal Faculté Des Sciences (Rabat)

    Rabat 2006 - 2013 Doctorat

    PhD in Neurosciences, Topic: “Lead toxicity consequences on basal ganglia activity
    and circadian rhythms in the rat: Electrophysiological, neurochemical and
    immunohistochemical approaches”
    The objective of thesis study was to determine the link between lead exposure and the development of the Parkinson disease.

  • Université Mohamed V AGDAL, Faculté Des Sciences Rabat (Rabat)

    Rabat 2004 - 2006 Diplôme des études supérieures approfondies


    Projet : l’impact du Plomb et du Cuivre sur l’intégration de l’information photique
    par le noyau suprachiasmatique chez le rat juvénile

  • Université Mohammed V AGDAL Faculté Des Sciences Rabat (Rabat)

    Rabat 2000 - 2004 Licence

    Biologie - Biologie animale

  • LYCEE IBN BATTOUTA (Rabat)

    Rabat 1999 - 2000 Baccalauréat

    Sciences Expérimentales - Sciences

Réseau

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