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Pierre-Eloi IMBERT

RUEIL MALMAISON

Electionseuropéennes 2024

RETROUVEZ GRATUITEMENTLe résultat des européennes à Walheim ainsi que le résultat des européennes dans le Haut-Rhin.

En résumé

Mes compétences :
Screening
Molecular biology
Chef de projet
Data analysis
Supervision of colleagues and apprentices
Daily management
Project coordination
Oncology
Hepatitis C
Drug Discovery
Dermatology

Entreprises

  • Novartis - Associate project manager

    RUEIL MALMAISON 2015 - maintenant * Strategic definition of low molecular weight identification projects :
    - Target validation (big picture, literature, assay definition)
    - Screening technology definition (state of the art screening readers and technologies, innovation)
    - Screening campaign assay development (full automation and miniaturization)
    - Hit identification (data mining, image analysis)
    - Hit-to-lead designation (teamwork, collaboration, leadership)

  • NOVARTIS Pharma - Scientist II

    2009 - 2015 * Management of screening campaigns to identify active compounds related to diverse pathologies * Labhead deputy for the operational and daily management ;
    * Development of several high content screening assays using stem and primary cells, using front runner imagers such as Opera or CV7000
    * Part of the team in charge of the implementation of the new automated screening platform STEP 2 designed for the automation of 2 Hammamatsu FDSS 7000
    * Development of a new cellular imaging technic for C5a receptor used by the project team as a basis to develop PK/PD assays for CSP nomination (project is now a PoC)
    * Identification of the first positive allosteric modulator of PGI2 receptor which has driven to several patents
    * Evaluation of BacMam technology (1 month Mini sabbatical in Novartis Horsham Research Center (England)) and implementation of the technology in Basel, successfully used on primary cells
    * Coach of technicians and apprentice: participate to the recruitment process, education and evaluation, operational guidance

  • NOVARTIS Pharma - Scientist I

    2003 - 2009 * Management of 10 to 15 HTS campaigns: organization, implementation and cost follow up ;
    * Project coordination: planning definition in term of needs, implementation of assays, data analysis and data presenting at project team meeting, coaching of 2 apprentices ;
    * Presentation of results on Hepatitis C project at international conference MIPTEC in Basel
    * Publication of an article about troubleshooting of Homogeneous Time Resolved Fluorescence in Assay and Drug Development magazine
    * Evaluation of new biochemical and cell based label free technologies (3 months mini sabbatical in Novartis Emeryville Research Center (California))

  • NOVARTIS Pharma - Scientific Associate

    2001 - 2003 * Management of several cellular and biochemical HTS campaigns: data analysis, presentation of results to my supervisor. Find out of the ability of RBL cells to be primed by ADP, which increase the calcium signal of GPCRs
    * Assay automation: development and evaluation of new innovating technologies, set up of new automated systems. Implementation of the first 1536 protein-protein interaction HTS campaign using Alphascreen

  • NOVARTIS - Assistant de recherche

    RUEIL MALMAISON 2000 - 2000 CDD en temps qu'assistant de recherche au sein de l'unité d'oncolgie de Novartis :
    - Etude de l'interaction p53-mdm2-p19ARF et dévelopement d'un essai de criblage phénotypique

  • NOVARTIS - Research Associate

    RUEIL MALMAISON 2000 - 2000 * Set up of an HTS adaptable screening phenotypic method by fluorescence transfer to study the pathway p53 - hdm2 - p14ARF. DNA and RNA purification, protein analysis

  • Pierre FABRE - Research Associate

    Castres 1998 - 1999 * Set up of a new method to extract native collagen from fish's skin

    * Education * Languages * Skills * Situation

Formations

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