Paris
RETROUVEZ GRATUITEMENTLe résultat des européennes à Blotzheim ainsi que le résultat des européennes dans le Haut-Rhin.
Scientist PhD drug discovery-oriented, specialized in GPCRs and ion channels. Topics of studies: screening, GPCRs (desorphanization, signaling and dimerization), ion channels (pharmacology and physiology), nervous system diseases, stereotactic surgery and animal behavior. Significant experience in therapeutic target evaluation and as a drug discovery team leader.
Skills: Project Management - Assay Development - Preclinical Pharmacology
- Cell-based assays: GPCR signaling, cytotoxicity assays, FACS, siRNA
- Cell culture: tissue slices, microexplants, primary neuronal cells, recombinant mammalian cells
- Molecular biology: RNA extraction, Q-RT-PCR, PCR, subcloning, gel agarose electrophoresis
- Stereotactic surgery: lesioning and cannulation
- Small molecules screening
- Histology: immunofluorescence and image analysis by confocal microscopy
- Patch-clamp electrophysiology: whole-cell recordings, neuronal activity
Mes compétences :
Project management
Cell biology
Animal behavior
Electrophysiology
High throughput screening
in vitro pharmacology
GPCRs
Drug discovery
Cell based assays
