Menu

Adeline MERGOUD

EVRY

En résumé

A dynamic, adaptive, open-­‐minded and fast-‐learning person with strong and acute interest and skills in Genetics and Aging on the model C. elegans.
I particularly enjoy collaborating and sharing with scientists from different origins and disciplines to improve my knowledge and contribute more forcefully to the projects.

Mes compétences :
Genetics
Molecular biology
C. elegans
RT-qPCR
CRISPR-Cas9
Design and construction of vectors
Project management
Teaching
Student's supervision
RNAi
Microinjection
Methods development and validation
State of art
Communication
Transgenesis
TEM
Fluorescent microscopy
Aging biology

Entreprises

  • AFM Téléthon - Voluntary work

    EVRY 2013 - 2015 Voluntary work for Téléthon: events for the annual fundraising initiative
  • Université Claude Bernard Lyon 1 - Students’ supervision

    Villeurbanne cedex 2013 - 2015 Supervision of 2 Master year 1 internships (2 x 7 weeks) and 1 Master year 2 internship (3.5 months)
  • UCB Lyon 1 and ENS Lyon - Teaching activities

    2013 - 2016 Genetics, Molecular Biology and Mathematics for biology

    Total: 68 hours of tutorial and 152 hours of lab work

    Teaching for 1st and 2nd years of bachelor’s degree in biology and master’s degree year 1 in Genetics, Cellular Biology and Pathologies, Université Claude Bernard Lyon 1, Lyon, France

    Teaching for 3rd year of bachelor’s degree in BioSciences, ENS Lyon, France
  • Forum “Biovision” - Co-­‐management

    Lyon 2012 - 2013 Meeting management, planning of «Next» program, supervision of participants
  • INMG – Institut NeuroMyoGène, CNRS UMR 5310 -­‐ INSERM U1217 -­‐ University of Lyon, France - Junior research scientist (PhD)

    2012 - maintenant Team « Génétique et Neurobiologie de C. elegans »
    Supervisor: Dr. Florence Solari,
    Team director: Pr. Jean-­‐Louis Bessereau,
    Project: “Identification of genes involved in the regulation of muscular aging and lifespan in C. elegans”
    New project developed:
    Deciphering mechanisms involved in muscle aging by using C. elegans
    Study of daf-­‐2/IGF, IR pathway and unc-­‐120/SRF and hlh-­‐1/MyoD

    Strategy:
    Site directed mutagenesis: CRISPR-­‐Cas-­‐9,
    Production of transgenic lines by microinjection in gonads
    Transgene’s integration (X-­‐ray & UV)
    RNA interference (RNAi by bacteria feeding)
    RNA extraction, RT-PCR, qPCR for transcriptomic validation
    Subcellular analyzis (actin, mitochondria morphology, autophagy)
    Monitoring of aging and locomotors activity in vivo (Lifespan test & thrashing assay)

    Statistical analyzis (XLStat, Prism), Results interpretation
  • CGPhiMC - Representative of the PhD students at the laboratory council

    2012 - 2015
  • CGphiMC, UMR 5534, University of Lyon, France - Internship for Master’s degree year 2

    2011 - 2012 Supervisor: Dr. Florence Solari

    Identification of subcellular changes involved during muscular aging in C. elegans, actin’s marking, lifespan
  • CGphiMC, UMR 5534, University of Lyon, France - Internship for Master’s degree year 1

    2011 - 2011 Supervisor: Benjamin LOPPIN

    Immunomarking + confocal microscopy of cells involved in capping of chromosomes in D. melanogaster

Formations

Réseau

Annuaire des membres :