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Alan URBAN

PARIS

En résumé

Brain Research through innovative technologies

My research is focused on 2 main area: control of brain activity and neuroimaging.
Our team seek to accelerate the development of the breakthrough technologies needed to build versatile and costless tools to decipher the role of specific cell types within the brain.

To address the challenges presented by neuroimaging, we develop a broad, interdisciplinary and translational science based on our own expertise and an unrivalled capacity work with scientists, governments, businesses and citizens alike.

For more details, please visit my website: http://alan-urban.fr

Skills :
• Brain Imaging
Voltage Sensitive Dye Imaging (VSDi)
Intrinsic Optical Imaging (IOI)
Laser Speckle/Doppler Imaging
functional micro-Doppler Sonography (fmDS)

• Electrophysiology
Patch-Clamp recording in mouse brain slices
Extracellular recording in freely moving conditions

• Optogenetics in slices and in alive rodents

• Molecular Virology : Aav design, production and purification, stereotaxic injection

• Molecular Biology including:
- RNA work: Cloning, in vitro transcription (cold or radiolabelled) of tRNA, rRNA and ribozymes
- DNA work: S.cerevisiae Yeast genetic manipulation, PCR, cloning (GATEWAY) - Microarray
- Protein work: Production in E.coli (batch) and Yeast P.Pastoris (fermentor, FPLC purification using
AKTA Explorer/FPLC/Prime with different chromatography column

Mes compétences :
Molecular Biology

Entreprises

  • NERF empowered by IMEC, VIB and KU LEUVEN - Group Leader

    2016 - maintenant Neuro-Electronics Research Flanders (NERF) is a young not-for-profit academic research initiative with the ultimate goal of forming a thorough understanding of brain function at multiple levels of detail ranging from cells and circuits to behaviour. New insights into the operation of brain circuits are empowered by the development of novel technologies that integrate neurobiology and nano-scale engineering. We will use and aim to develop novel electronic, chemical and optical tools to monitor and manipulate brain circuits with high spatial and temporal resolution. In the long term the basic research at NERF is expected not only to inspire scientists to simulate brain networks, but also to lay a scientific framework to develop novel medical applications for the diagnosis and treatment of neurological disorders.
  • CHSA - Centre de Psychiatrie et Neurosciences - INSERM U894 - Neuroscientist - Group Leader

    2012 - 2015 Research Team Optogenetics and Brain Imaging
  • Laboratoire de Neurobiologie - CNRS UMR 7637 - ESPCI - MDC Ville de Paris

    2009 - 2012
  • Laboratoire de Neurobiologie - ESPCI - Postdoctorant CNRS

    2008 - 2009
  • Laboratoire AREMS - CNRS UMR 7214 - Doctorant

    2003 - 2008

Formations

  • Université Nancy 1 Henri Poincaré

    Vandoeuvre Les Nancy 1998 - 2008 Biologie Moléculaire et Cellulaire

    http://www.uhp-nancy.fr/recherche/laboratoires/rechercher_un_laboratoire/laboratoire_arn_rnp_structure_fonction_maturation_enzymologie_moleculaire_et_structurale
  • Lycee Jacques Marquette

    Pont A Mousson 1995 - 1998 Science - Mention biologie

    http://www.ac-nancy-metz.fr/Pres-etab/JacMarquette/

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