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Anaïs PASQUIER

LYON

Electionseuropéennes 2024

RETROUVEZ GRATUITEMENTLe résultat des européennes à Lyon ainsi que le résultat des européennes dans le Rhône.

En résumé

Graduated from the UTC, I have a 3-years experience in the Biotech-Pharma industry.
I am specialized in the study of therapeutical proteins (monoclonal/polyclonal antibodies, insulin and peptides):
> from their production (in vitro: bioprocess development - in vivo)
> for their physico-chemical characterization (analytical development)
> for their optimization (by nanotechnologies)
> to efficacy(in vitro) and preclinical studies (PK)

My strong technical skills (DUT training and laboratory work) and management skills (UTC training and project manager position) are two of my major assets to manage R&D projects
(e.g. academic-industrial multi-partners ISI (BPI-France) program and test release development).

As the "Quality Coordinator in the R&D department", I also had the opportunity to develop and implement quality within project management.

Please feel free to contact me whether you wish to discuss further about my background or any related topic, I would be pleased to discuss with you.
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Key words: Bio-Pharmaceutical Industry - Therapeutical Proteins - Monoclonal and Polyclonal Antibodies - R&D - Project Management

Entreprises

  • Fab'entech - R&D Projects Engineer

    2014 - maintenant > Development of F(ab')2 Fragments from Specific Polyclonal Immunoglobulin against Infectious Emerging Disease.

    - Project management of a multi-partners (academics/industrials) ISI-BPI France program
    - Development of a quantitative ELISA activity test for clinical batches release
    - Implementation of a pharmaco-kinetic (PK) study
    - Efficacy studies (in vitro/in vivo)
    - Laboratory running
    - Implementation of quality tools and conciousness raising about the good practices

  • Merck Serono - R&D Bioprocess Engineer

    Lyon 2014 - 2014 > Fed-Batch Platform Optimization for Monoclonal Antibody Production in Mammalian Cells Culture

    - Impact of culture parameters on the "critical quality attributes" by DoE
    (process parameters-medium and feeds composition, formulation and optimization)
    - Stability studies and antibody characterization
    - Overview of internal projects and bibliography study to identify the "critical process parameters": Transverse project in parternship with Analytical and Downstream services
    - Lab meeting presentations on powerpoint and poster in workshop

  • Equipe activités microbiennes et bioprocédés (EA 4297) - In Charge of Experimental Study

    2013 - 2014 > Optimization of Cellulolytic Microbial Culture

    - Bacterial cultures
    - Optimization of culture media/conditions
    - Enzymatic activity study in bacteria

  • GAEC l'Egaillerie - Feasability Study

    2013 - 2013 > Changing of milking machine
    - Economic, ergonomic and technical feasibility

  • BIOPRACTIS Training Center - Trainee for Continuing Education

    2012 - 2012 > GMP and Handling in Clean Rooms Training

    - European and Americain good manufacturing practices for bio-therapeutics (BPF-cGPM-ICH)
    - Moving/Action/Clothing/Hygene rules related to classified environnements
    - Control monitoring in classified production area

    Know more: http://www.biopractis.com/

  • Carlina Technologies - Engineer Assistant

    2012 - 2013 > Innovative System Development for Long Term Release of Insulin

    - Formulation and optimization of therapeutical proteins nanoparticles
    - Nanoprecipitation scale up assay
    - Encapsulation of insulin nanoprecipitates into microspheres
    - Release studies of insulin from microspheres
    - HPLC method method developement to quantify insulin at the different formlations tages (i.e. nanoprecipitated, loaded into microspheres and released from microspheres)
    - Physicochemical characterization of the formulated products

  • Laboratoire de neurobiologie et transgénèse UPRES 3143 - Laboratory Technician

    2011 - 2011 > Targeting of Glioma Cells by Lipidic Nanocapsules with Anti-Glioma Peptide
    Study for Balzeau et al. (2013)

    - Uptake and targeting studies: using primary cell cultures and cell line cultures, studying mouse brains

    Know more: Balzeau et al. (2013)

Formations

  • Université De Technologie De Compiègne

    Compiegne 2011 - 2013 Génie Biologique

    [Biological Engineering Diploma - Master Degree]
    [Design and Innovation of BioProducts Specialization]

    The UTC gives the opportunity to have customized courses.
    Keen on biotechnology and interested in project management, I chose to study courses related with those fields:
    > Molecular biotechnologies and genetic engineering/ Applied microbiology/ Cellular biology and immunology/ Protein engineerin

  • IUT - Université D'Angers (Institut Universitaire De Technologie)

    Angers 2009 - 2011 Génie biologique

    [Engineering Core Studies Diploma in Biological Engineering]
    [Biological and Biochemical Analysis Specialization]

    - Quantitative and qualitative biochemical analysis and experiments design
    - Chromatographic and spectrometric analyses and robot handling: HPLC, CPG, flow cytometer...
    - Cell culture: mammalian (primary and cell line), microbial and plant
    - Animal experimentation for pharmacological

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