Gaëlle LE GOFF

En résumé

Entreprises

• Massachusetts Institute of Technology - Research Scientist

  2012 - 2015 Located in Cambirdge, MA (USA)
  
  Leads a multidisciplinary collaborative project between
  * Novartis Institute for Biomedical Research, Screening group (for Lead Finding activities) and
  * Massachusetts Institute of Technology, Department of Chemical Engineering, Doyle lab
  
  (see description above)

• Novartis - Research Scientist

  RUEIL MALMAISON 2012 - 2015 Located in Cambirdge, MA (USA)
  
  Leads a multidisciplinary collaborative project between
  * Novartis Institute for Biomedical Research, Screening group (for Lead Finding activities) and
  * Massachusetts Institute of Technology, Department of Chemical Engineering, Doyle lab
  
  ▪ Designs, plans, performs and analyses research studies
  Developed multiplex bioassays on encoded hydrogel microparticles
  - Designed strategies for graphical encoding and decodinf of particles
  - Automated workflow for particle assay, reading and analysis algorithm on HTS equipment
  - Designed a microfluidic chip for high-throughput flow-lithography of hydrogel encoded particles
  Investigated applications of hydrogel photo-patterned structures for cell imaging and cell culture
  Performed gene expression studies on bead-based arrays
  
  ▪ Initiates and manages internal and external collaborations with experts, engineers, IT specialists and vendors
  
  ▪ Presented research projects at international conferences (3 posters) and in peer-reviews publications

• AXOscience, Lyon (France) -  Co-founder & Consultant – Scientific Research And Development

  2010 - maintenant High-throughput and multiparametric analysis tools dedicated to the characterization of biological samples
  
  * Involved in the creation of the start-up
  * Contributed to development of the core technology
  * Contributed to automation and robotics
  * In charge of a collaborative project dedicated to the development of an image analysis software

• PRES UNIVERSITÉ DE LYON - Teaching Assistant ("monitorat")

  LYON 7EME 2008 - 2011 * tutorials and practical chemistry lessons and evaluations (inorganic chemistry, kinetics, organic chemistry)
  * undergraduate level ~ 170 hours
  * master level ~ 30 hours

• Université Claude Bernard Lyon 1 - Graduate Student & Teaching assistant

  Villeurbanne cedex 2008 - 2011 PhD in Chemistry (2011)
  Fellowship awarded from the French Ministry of Higher Education and Research.
  
  Molecular and Supramolecular Chemistry and Biochemistry Institute (ICBMS)
  Laboratory for “Enzyme engineering, biomimetic membranes, supramolecular assemblies”
  
  • Developed DNA and protein microarrays for low cost multiplex bioassays
  - spotting of medium density oligonucleotide and protein planar microarrays
  - optimization of immobilization chemistry on membranes and polymers (PolyshrinkTM)
  - target quantification using colorimetric detection and enzymatic amplification
  - assay automation using microplate format and high-throughput robotics
  • Led a collaboration with the French Blood Center to develop low-cost high-throughput blood group genotyping on oligonucleotide microarrays (single nucleotide polymorphism genotyping, multiplex PCR)
  • Applied on chip immunoassays to multiplexed allergy diagnosis
  • Contributed to patent and grant writing and to the launch of a spin-off company
  • Presented at international conferences (1 talk, 2 posters)
  

• Université Claude Bernard Lyon 1 - Research Intern

  Villeurbanne cedex 2008 - 2008 Developed microarrays and surface chemistries for nucleic acid detection using chemiluminescence and colorimetric assays

• University of Sydney, Australia - Research Intern

  2006 - 2006 Established a fluorescence method to quantify the orientational polarisability of lipid membrane surface

• Bio-organic Chemistry and Molecular and Cellular Biotechnology Laboratory, ENSCP / Paris V - Reserch Intern

  2005 - 2005 Optimized automated synthesis of a bank of lipid triazoles for biological applications

Formations

• Faculté De Médecine Pierre Et Marie Curie

  Paris 2016 - maintenant Diplôme Universitaire Génie Biologique et Médical
  
  Valorisation de la recherche et de l’innovation biomédicale
  
  Learn about the socio-economical and regulatory environment of biomedical innovation to promote innovation and research

• Ecole Normale Supérieure Sciences ENSET

  Lyon 2004 - 2008 Degrees
  Licence - 2005
  Agrégation (Sciences Physiques Option Chimie) - 2007
  Master 2 Recherche - 2008
  
  Activities
  Member of ENS Lyon’s Student Committee (2005).
  Managed the organization of the 2 major student events: "Week-end d'intégration" ~ 10k€ budget, 300 participants, 3 days; Gala (Prom) organization; ~ 10k€ budget, 15-person

• Lycée Louis-Le-Grand (Paris 5ème)

  Paris 2002 - 2004

Réseau

• Céline MANDON

• Delphine FOUGEROUSE

• Gaelle CATANANTE