. The prime interest of my research in neuroscience is to decypher the pathophysiology of several human pathologies using rodent models. I've been working in two great branches of neuroscience: (1) psychiatric and neurodegenerative diseases (especially schizophrenia); and (2) visceral pain (especially irritable bowel syndrome -IBS- and inflammatory bowel disease -IBD-).
. So far, my research has outlined (1) the critical role of the brain endocannabinoid system in social withdrawal (negative symptoms of schizophrenia); and (2) the involvement of nerve growth factor (NGF) interplay with ion channels capable of sensing acidity in the sensitization of colon nervous pathways conducting pain sensation (abdominal symptoms in IBS and IBD).
. As a researcher, I believe conducting good research relies on three major keystones: (1) the will to consider and integrate the clinical data as a whole rather than focusing on very restricted and isolated targets; (2) the relevance of the working hypotheses to the clinical reality of the human diseases studied; and (3) the use of multidisciplinary (and transdisciplinary, when possible) approaches to widen our scientific gaze and to get robust and reliable results.
. I want to fit into dynamic private or public institutions where I will be able to use my scientific knowledge and my experience in the monitoring of scientific bibliography, in project set-up and development, and in management to work on new promising hypotheses highly relevant to human diseases. Work ethics and bench-to-bedside research strategy are a definitive plus.
Mes compétences :
Biologie moléculaire
Veille scientifique
Immunohistochimie
Pharmacologie
Physiologie
Neurosciences