Mes compétences :
Docking
Organic chemistry
Pharmaceuticals
3D Modeling
Project Management
Analytical chemistry
Medicinal chemistry
Entreprises
Antabio
- Senior Medicinal Chemist
Labège2013 - maintenantDevelopment of small molecule compounds for the treatment of MDR gram-negative bacteria:
- Design, synthesis and development of novel antibiotics adjuvants to enhance the effectiveness of existing antibiotics
- Supervision and management of new research projects
- Development of API's new synthetic routes
- Bibliographic studies, reports preparations and results presentations
Pharmaleads
- R&D project manager - Chemistry
2010 - 2013Design, synthesis and development of metalloproteases inhibitors in the field of endogenous analgesia and antidiarrhea
- Supervision and management of new research projects: Design, computational visualization (Discovery Studio 3.1) and docking (Gold 5.1) of novel therapeutic targets
- Multi-step organic synthesis
- Development of API's new synthetic routes: PL37 (phase II) et PL265 (phase I)
- Bibliographic studies, reports preparations and results presentations
- Environment, Health and Safety (EH&S) specialist
Institut de Chimie des Substances Naturelles (ICSN) - CNRS
- Research Engineer - Chemistry
2009 - 2010Design and synthesis of Calcium Sensitive Receptor antagonists, derivatives of Calhex231 (treatment against osteoporosis)
Biodesign Institute - Arizona State University (USA)
- Research Associate - Chemistry
2007 - 2009- Synthesis of natural Topopyrones and analogues as potential Topoisomerase I and II inhibitors (antitumoral agents)
- Design and synthesis of Verticipyrone analogues as potential mitochondria complex I inhibitors (antiparasitic agents)