Vesna CUPLOV

En résumé

Entreprises

• Commissariat à l'Energie Atomique (CEA) - Ingenieur-Chercheur

  2015 - 2016 A new approach in cancer treatment is the use of nanoparticles for the induction of intracellular hyperthermia. Near infrared absorbing nanoparticles enhance photothermal therapy of tumors. Computational modeling is an important tool for investigating and optimizing parameters such as nanoparticle size and shape, excitation wavelength and tissue properties. I develop the Geant4-based simulation code GATE (http://www.opengatecollaboration.org) to model nanoparticle mediated hyperthermal cancer therapy.
  

• University College London - Research Associate

  2013 - 2015 Idiopathic Pulmonary Fibrosis is an interstitial lung disease characterized by an increase in the quantity of extra cellular matrix and the destruction of parenchyma structure. There is no effective treatment. There has been an increased interest in imaging pulmonary disorders using Positron Emission Tomography (PET) techniques. This work involved studying the PET radiotracer uptake in lung regions exhibiting obvious fibrosis and correcting PET images for the ‘tissue fraction effect’ which has been extended to include the blood component of the lung tissue. It also involved respiratory gating (gate the data into different motion states) of lung PET/CT data. Data driven gating of 4D-CT data was performed using the principal component analysis.

• Commissariat à l'Energie Atomique (CEA) - Ingenieur-Chercheur

  2011 - 2013 Optical imaging is currently drawing growing interest for molecular imaging, as a non-invasive, efficient and low-cost imaging technique allowing for real time study of biological processes. Based at the Service Hospitalier Frédéric Joliot in Orsay, I developed an extension to the Geant4-based simulation code GATE (http://www.opengatecollaboration.org) to model optical imaging experiments such as bioluminescence and fluorescence. Monte-Carlo simulations of optical imaging are computationally demanding. Recently, Graphics Processing Units (GPU) became a cost-effective solution to access to high power computation. I extended GATE to support optical imaging simulations using GPU architectures.

• Rice University (Houston, Texas, USA) - Post-doctoral research associate

  2008 - 2010 Based at the European Organization for Nuclear Research (CERN) in Geneva (Switzerland), I was appointed as the co-convener of the "Compact Muon Solenoid Tracker Simulation group" and held the position for two years. I was personally in charge of the pixel detector simulation and was a member of the USCMS team in charge of commissioning the pixel detector after installation at CERN. I participated in data acquisition shifts and was appointed as "Tracker Offline shift leader" whose responsibilities were to certify the data collected by the experiment. I extensively studied the Top quark production cross section in early data by looking for semileptonic decays of the top quark pairs with reliance on the search for simple secondary vertices to find b quarks.

• Purdue University Calumet (Hammond, Indiana, USA) - Post-doctoral Research Associate

  2006 - 2008 Based at the Fermi National Accelerator Laboratory (Fermilab) near Chicago, I was a member of the Compact Muon Solenoid (CMS) experiment at CERN and the DO experiment at Fermilab. I was responsible of the burn-in tests (thermal cycling) of the CMS forward pixel modules at the Fermilab Silicon Detector facility to assure the quality of the sensors used to build the pixel detector. I was in charge of the GEANT4 simulation of the CMS forward pixel detector geometry. Regarding physics analysis, I was one of the leaders of the search for new particles decaying into a Z boson and a photon using the Tevatron collision data collected with the DO experiment. The results of this analysis were limits on theoretical models that predict these type of particles requiring a thorough statistical analysis for interpretation ("Search for a scalar or vector particle decaying into Zγ in ppbar collisions at center of mass energy of 1.96 TeV").

Formations

• Université Aix Marseille 2 Mediterranée

  Marseille 2000 - 2004 Doctorat en Physique
  
  Dissertation title: Isospin breaking and radiative corrections in semileptonic kaon decays.
  
  The theory of strong interaction, Quantum Chromo Dynamics (QCD) is not valid in the low energy domain because a perturbative approach as function of the strong coupling constant is not possible. Pions and kaons are understood as resulting from the dynamic breaking of an approached symmetry of QCD: the chir

Réseau

• Abdesslem IDI

• Anouar MEKKAS

• Christophe PIARD

• Ingeliance Technologies - AGENCE DE BORDEAUX

• Julien PACHET

• Mohamed ASLAN