Cécile MULLER

En résumé

Entreprises

• Laboratory of Environmental Microbiology - University of Caen - Assistant Professor

  2011 - maintenant

• Pall Genesystems - Chef Project

  2010 - 2010

• Institut Pasteur, Unité de Pathogénèse de Helicobacter, Paris - Research scientist/Chercheur

  2008 - 2009 My research topic was the study of a transcriptional regulator NikR of the pathogen bacteria Helicobacter pylori, involved in stomach cancer. This regulator is essential for the virulence of the bacteria and is activated by nickel available in the stomach. I identified new NikR target genes and I followed their expression to specify the role of NikR in bacteria pathogenicity. This study was a part of a collaboration with 2 research teams in Grenoble (ESRF and CEA).
  I also was in charge of the real-time PCR material and training.

• Laboratory of Medecine and Microbiology, University of Washington, Seattle, USA - Research scientist/Chercheur

  2007 - 2008 I studied the activation mechanism of the SigmaE factor by acid pH in Salmonella enterica sv. Thyphimurium. This factor allows the transcription initiation by RNA polymerase during heat stress, and is important for Salmonella survival in macrophages.
  I also managed the biochemical platform of the lab.

• Laboratoire de Microbiologie de l'Environnement, INRA, Université de Caen-Basse Normandie, Caen - Research student/ étudiante

  2003 - 2006 I identified two-component systems involved in Enterococcus faecalis survival in macrophages and in virulence in mice. I determined the role of these regulatory systems in E. faecalis stress response.
  I also helped for student education by doing some lessons.

• Laboratoire de Microbiologie Alimentaire, INRA-ENSAR, Rennes - Trainee/stagiaire

  2003 - 2003 I perfected RT-PCR experiments in Staphylococcus aureus.

• Laboratoire de Microbiologie de l'Environnement, INRA, Université de Caen-Basse Normandie, Caen - Trainee, research student/stagiaire, étudiante

  2001 - 2002 I had 2 training courses in the "Laboratoire de Microbiologie de l'Environnement" during 2001 and 2002 years. I studied the glycerol metabolism of a cider bacteria Lactobacillus collinoides, and I characterized a sigma factor involved in extracytoplasmic response of E. faecalis.

• Laboratoire de Biologie Moléculaire et Cellulaire, INRA, Bordeaux - Trainee/stagiaire

  2000 - 2000 I studied the molecular biology technics in Spiroplasma citri, a vegetal pathogen.

Formations

• Université Caen Basse Normandie

  Caen 2003 - 2006 Two-component systems involved in stress response and pathogenicity of Enterococcus faecalis
  
  PhD Biology Molecular and Cellular Aspects/Thèse Aspects Moléculaire et Cellulaire de la Biologie

• Université Caen Basse Normandie

  Caen 2001 - 2002 Characterization of a sigma ECF factor of Enterococcus faecalis
  
  MSc Fundamental and Applied Microbiology/DEA Microbiologie Fondamentale et Appliquée

• Université Bordeaux 2 Victor Segalen

  Bordeaux 1999 - 2001 Biologie Cellulaire et Moléculaire, Génétique
  
  BCs in Cellular Biology, Physiology/Licence-maîtrise Biologie Cellulaire, Physiologie

• Université Caen Basse Normandie

  Caen 1997 - 1999 DEUG Biologie

Réseau

• Bertrand COISSAC

• Cyrille DUBOSC

• Gaëlle LEBORGNE

• Maud GROJEAN

• Maxime BOUTROIS

• Mohamed ELAYEB

• Patrice CHABLAIN

• Philippe PUJOL

• Sylvie AUBERT

• Vincent BREDECHE