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Charlotte LE MERDY

TOULOUSE

En résumé

Dynamic, team player, proactive with good interpersonal skills and ability to summarize. I am currently
working in a French biotechnology company with strong international connections.

Mes compétences :
Purification protéique (AEX, HIC)
Manipulation des systèmes AKTA
Technique analytique QC
Analyses biochimiques
Gestion de la qualité
Immunization
Biotechnology
Team player
Western Blotting
Process Transfert
Standard Operating Procedure
SDS
Quality Assurance
Chromatography: AEX/IEX/HIC/SEC
Pack office
Unicorn
QuantityOne
PDQuest
GLP
ELISA
DSP
Ultrafiltration

Entreprises

  • GENTICEL - Scientist Bioprocess and Analytical development

    2011 - maintenant Scientist Bioprocess at GENTICEL, a privately-owned company focused on therapeutic HPV vaccine(Listed on Euronext since April 2014 ).
    - Management of a process transfer at pilot scale to an international CMO, including documentation revision/approbation and training period on site.
    - Optimisation of Down Stream Process (DSP) steps with the aim to improve protein purity and recovery yields; work on Inclusion Bodies (IB) processing, chromatography and Ultrafiltration steps
    - Responsible of the FPLC system; creation of Unicorn method, maintenance, troubleshooting, technical contact with GEHC.
    - Purification of vaccines candidates for a screening campaign
    - Actively involved in the management of the quality system of the bioprocess team
    - Redaction of study and experiment reports (written in English)
    - Regular presentation to the team.

  • GENTICEL - Scientist Quality Control and Analytical Development

    2009 - 2011 Set up and optimisation of a vaccine formulation under lyophilised form. ;
    - Development and application of vaccine stability studies. ;
    - Optimisation and development of analytical characterisation assays. ;
    - Management of subcontractors for proteomics analysis (MALDI-TOF, LC-MS/MS).

  • GENTICEL - Trainee

    2008 - 2009 Final year internship at GENTICEL: Development of an analytical test to improve the proteomic characterisation of vaccines candidates.
    - Optimisation of a 2-Dimensional Gel Electrophoresis method (2D-PAGE)
    - Characterisation of the 2D vaccines profiles by Western-Blot (WB) and proteomic cartography (MALDI-TOF)

  • SANOFI - Trainee

    Paris 2007 - 2008 Research studies focused on the Kinases enzymes and their role in the inflammatory mediation occurring in a heart stroke.
    - Development of in vitro cellular assays to evaluate Kinases inhibitor candidates
    - Investigation on cellular expression localisation by immunofluorescence

Formations

  • School Of Agrifood And Forestry Science And Engineering (Lérida)

    Lérida 2008 - 2009 International exchange of 6 months in Biotechnology degree
    Key modules: Virology, Bioreactor, Protein engineering.

  • University Of Technology Of Compiègne (UTC) (Compiegne)

    Compiegne 2004 - 2009 Masters Degree of engineering in Biotechnology

    Key modules: Upstream and Downstream process, immunology, Biochemistry, Molecular Biology, communication, project management.

Réseau

Annuaire des membres :