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Jérôme COURTÊTE

Roussay,

En résumé

Ayant passé ma thèse en biologie moléculaire et cellulaire en début d'année. Je suis actuellement en post-doc en Irlande, au sein de l'institut NCBES (National Centre for Biomedical Engineering Science) dans l'université de Galway (NUIG).
Au cours de ce travail post-doctoral, j'espère acquérir de nouvelles compétences (management, techniques ...) qui me permettront à terme d'intégrer le département recherche et développement d'un grand groupe pharmaceutique.

Mes compétences :
Molecular Biology
Project managment softwares
Cell Biology
Protein Production
Protein purification
Flow cytometry
Analytical assays
Cell Line Development
Transient expression
Biologie moléculaire
Biotechnology

Entreprises

  • Vivalis - Head of protein production and purification group

    Roussay, 2013 - maintenant My activities essentially consist to manage the production/purification/characterization of recombinant proteins on CHO-based expression platform to support clients projects or internal requirements.
    I'm also in charge for the improvement of the protein production platform including interactions with USP, DSP and analytical developments.

  • Vivalis - Project manager in cell biology group

    Roussay, 2009 - maintenant Development of the EBx platform for the production of therapeutic monoclonal antibodies

    Project leader, I directly supervise an engineer assitant.
    I'm currently in charge of managing projects for the development, production and purification of monoclonal antibodies. I also write laboratory activity report and manage laboratory meetings.

  • NCBES National University of galway - Post-doctoral position

    2008 - 2009 Post-doctoral position NCBES National University of galway
    NUI Galway

    Établissement éducatif; secteur Enseignement supérieur

    janvier 2008 – juin 2009 (1 an 6 mois)

    After completing my thesis in January 2008, I directly started in February a post-doctoral position in the Institute NCBES (National Centre for Biomedical Engineering Science) in the University of Galway (Ireland).
    I worked to develop new therapies for cancer. My researches focused in particular on colon cancer, although their application field can certainly be extend to other cancers.
    Briefly, it has been reported that certain proteins derived from the TNF family have anticancer properties. My job was to potentiate the anticancer effects of a protein derived from this family by genetic engineering, mutagenesis and test its effectiveness on cancer cell lines in vitro and then on mouse models. Mesenchymal stem cells (MSCs) have been shown to home to tumour sites and could potentially act as a shield and vehicle for a tumouricidal gene therapy vector.We transduced MSCs with adenoviral vector expressing a soluble form of TRAIL and show the apoptosis-inducing activity on colon carcinoma cells in vitro and on tumour developped on mouse models.
    This postdoctoral experience allowed me to greatly improve my English, I also expanded my field of expertise especially with the production and purification of adenoviral vectors, and the use of tools such the FACS or Guava. Otherwise, I was also managing a PhD student.

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