Marie-Cécile DIDIOT

En résumé

Entreprises

• Novartis Institut for Biomedical Research - Post-doctoral fellow

  2008 - maintenant Post-doctoral fellow, Center of Proteomic and Chemistry, Lead Finding Platform.
  Developing and implementing chemical screen using cellular models to elucidate compound modes of action and to discover novel targets and leads. Experimental design, molecular biology for cells generation and HTS assay development for disease target specific assays.
  Collaborating with Novartis Scientists of diverse disciplines to advance high visibility therapeutic drug discovery programs.

• Ph-D student CNRS - Chercheur

  2004 - 2008 Ph-D in molecular and cellular biology "Implication of the Fragile X Mental Retardation Protein, FMRP, within translation regulation".
  Peer reviewer:
  - A novel function for fragile X mental retardation protein in translational activation. Plos Biol, 2009
  - Cells lacking the fragile X mental retardation protein (FMRP) have normal RISC activity but exhibit altered stress granule assembly. MBC, 2009
  - The G-quartet containing FMRP binding site in FMR1 mRNA is a potent exonic splicing enhancer. NAR, 2008

Formations

• University Louis Pasteur

  Strasbourg 2004 - 2008 Molecular basis of the Fragile X Mental Retardation Protein functions

• University Louis Pasteur

  Strasbourg 2003 - 2004 Molecular basis of the Fragile X Mental Retardation Protein functions
  
  Master II degree

• University Henri Poincare

  Nancy 1998 - 2003 Master I degree

• High School "Les Haberges" (Vesoul)

  Vesoul 1995 - 1998 General scientific high school diploma

Réseau

• Elise SIMON

• Honorio DA SILVA

• Karim HNIA

• Malayphone NGUYEN

• Natacha DREUMONT

• Patricia MARQUES

• Thierry CAILLAT