Stéphane DEFOSSE

En résumé

Entreprises

• SAS Defosse & Co - CEO of SAS Defosse & Co

  2014 - maintenant Opportunity for a professional and family project with the take-over of a company (Lot-France)
  - Up to 15 people employed
  - Turnover increased by 22% and expenses decreased by 10% in one year
  - Process to sale the company on going
  

• GlaxoSmithKline - Site Director

  Marly-le-Roi 2013 - 2013 One of the largest production site in the GSK network. Specialized in respiratory medicines. The site employs 1000 people and produces for 135 markets around 120 million of units per year.
  - Steer the execution of the strategy and deliver the site objectives
  

• GlaxoSmithKline - Manufacturing Strategy Director Oncology

  Marly-le-Roi 2012 - 2012 Follow the different steps of drugs development with R&D, analyse with Medical & Commercial the potential ambition, then prepare the manufacturing network capacity (internal or CMO)
  - Follow the oncology portfolio
  - Anticipate and propose solution for preparing the industrial network
  

• GlaxoSmithKline - Head of change management and continuous improvement

  Marly-le-Roi 2011 - 2012 Member of the French Commercial Executive Team (FET). Objective: Engage the French organization in a transformation through Accelerated Delivery Programme. (Strategy deployment, develop Operational Excellence for growing and organisation simplification)
  - Lead the construction of the strategy with the FET and the deployment throughout all the organization
  - Engage French commercial organization in new ways of working with lean approaches
  - Lean approach on Seretide (Asthma product) to stop sales erosion and be back to growth (+1.7% vs previous year)
  

• GlaxoSmithKline - Production Director

  Marly-le-Roi 2008 - 2011 Member of the Site Leadership Team. In charge of the Aerosols and tablets units.
  Lead a transformation
  - Influence the site organization and build the production transformation
  - Lead the change, motivate people whilst staff decreased & volume increased
  - Annual production of 80 million aerosols and 87 million tablets
  - Deliver 35% productivity between June, 2009 and December, 2010 with 50% reduction of BNRFT and deviations
  

• GlaxoSmithKline - Operational Excellence Director

  Marly-le-Roi 2005 - 2008 Member of the Site Leadership Team (SLT).
  Lead the site vision and the associated strategy building with the SLT. Influence the site culture on continuous improvement through the Lean & 6 Sigma programs.
  - Develop Lean sigma experts, data managers, statisticians, knowledge manager
  - Deliver 30% productivity savings and cost of poor quality decreased by 50% in 3 years
  - Lead the OE capabilities development for the site: 2 master black belts, 5 black belts, 50 green belts and 200 yellow belts certifications with our Lean Academy.
  

• GlaxoSmithKline - Production Leader

  Marly-le-Roi 2002 - 2004 Aerosol production for Asthma treatment. Manufacturing and packaging (FDA, ANSM, Japan inspections…). Productivity projects led to reach the challenge (Saving of 15% on COG’s).
  - Staff of 250 people
  - Production in 3 shifts / 7 days per week
  - Deliver a volume increased of 60% in 2 years with 80 millions aerosols manufactured in 2004
  

• GlaxoSmithKline - Value Stream Deputy Director

  Marly-le-Roi 1994 - 2001 Value stream of 170 people which manufactured solid dose, suppositories and devices packaging, including production, maintenance, QC, logistic and validation.
  Different responsabilities during this period, workshop manager, product transfer manager, Validation, Continuous Improvement leader, logistic manager

Formations

• ITIIHN ITII-HN

  Evreux 1991 - 1994

Réseau

• Bragard-Breyer CHRISTOPHE

• Celine CHEVALLIER

• Damien BICOT

• Florent BIRIEN

• Frederic PRINGAULT

• Herve BOULNOIS

• Karine SMADJA

• Nicolas RAGOT

• Stephane COUSIN

• Vincent BUDIN