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Caroline DUBROCA

Labège

Electionseuropéennes 2024

RETROUVEZ GRATUITEMENTLe résultat des européennes à Toulouse ainsi que le résultat des européennes en Haute-Garonne.

En résumé

PhD with relevant experience in Drug R&D with over 10 years of experience in non-clinical pharmacology within both academic institute and private companies as project manager.

Strong research background in cardiovascular diseases (hypertension, heart failure and pathological cardiac hypertrophy) and vascular biology (endothelial dysfunction and flow-induced dilation).

Skills in operational managment and service offer establishment in the field of cardiovascular diseases and complications.

Mes compétences :
Project coordinator
Preclinical development
Business development
Cardiovascular physiology
Project management
Research
Cell biology
Microsurgery
Vascular reactivity
Molecular Biology

Entreprises

  • Cardiomedex - Project manager / Head of preclinical platform

    Labège 2011 - maintenant Cardiomedex is a CRO specialized in cardiovascular diseases and complications.

    In charge of:
    - Project management (budget, planification, study plan, study follow-up, data analysis, final reports)
    - Operational management
    - Customer relationship management
    - Consultancy work
    - Service offer establishment and brochure conception
    - Business database and web site development in collaboration with Business Development and Marketing Manager

    Specific expertise leveraging the preclinical platform of Cardiomedex:
    - Myocardial infarction (LAD coronary artery ligation)
    - Pressure overload-induced cardiac hypertrophy (thoracic aortic banding)
    - Heart failure
    - Hypertension
    - Combined diseases models with Hyperlipidemia, Obesity, Diabetes
    - Cardiac function assessment (pressure catheter, echocardiography, telemetry monitoring...)
    - Vascular reactivity (flow-mediated dilation, pressure-induced constriction, pharmacology...)

  • Inserm - Researcher in Heart Failure Division, Institute of Cardiovascular and Metabolic Diseases, Toulouse

    PARIS 13 2011 - 2011 Theme: Heart failure and cardiac hypertophy

    Duties: Project research monitoring, Achievement of scientific experiments

    Technical skills: Coronary artery ligature induced myocardial infarction, thoracic aortic constriction, left ventricular pressure/volume loops analysis, echocardiography...

  • Inserm - Researcher in Heart Failure Division, Inserm U970 - Paris Cardiovascular Research Center

    PARIS 13 2009 - 2010 Theme: Heart failure and cardiac hypertrophy

    Duties: Project research monitoring, Achievement of scientific experiments

    Technical skills: Micro-surgery, telemetry device implantation and monitoring, adult cardiomyocytes isolation for calcium transients and contractility assessment...

  • SERVIER - Non Clinical Study Manager

    Suresnes 2008 - 2009 In charge of:
    - Project monitoring
    - Competitive intelligence
    - Evaluation of offers for sale or co-development of molecules

    Skills acquired: Preclinical development, Project managment

  • SERVIER - Post-doctoral Reseacher

    Suresnes 2007 - 2008 In charge of project research influence of aging on flow-induced calcium response and NO pathway in endothelial cells

    Skills acquired: Endothelial cells isolation and culture, calcium signaling assessment in response to shear stress, Fluorescence imaging for intracellular calcium measurements

  • Unit of Pharmacology and Therapeutics, UCL (Bruxelles) - Post-doctoral Researcher

    2005 - 2006 Director: Dr Jena-Luc Balligand

    In charge of research project: Role of endothelial nitric oxide synthase (eNOS) in cardiac stem cells differenciation

    Skills acquired: Neonatal cardiomyocytes and cardiac stem cells isolation, cell culture, Immunochemistry...

  • Inserm - PhD student

    PARIS 13 2001 - 2005 Supervisor: Dr Daniel Henrion, Director: Dr Alain Tedgui

    Theme: Myogenic tone mechanotransduction: pathways and pathophysiological implications

    Skills acquired: Vascular reactivity and specially flow-mediated dilation and pressure-induced constriction assessment in resistance arteries mounted in a pressure myograph, Micro-dissection, Molecular biology...

  • Pierre Fabre - Trainee

    Castres 2001 - 2001 Characterization of calcitonin gene related peptide-induced relaxation in cerebral arteries

Formations

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