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Omegachem Inc.
- Director
2016 - maintenant
Responsible for Chemical Process Services at Omegachem Inc.
• Manage ressources, prepare quotations and plan daily project activities to deliver pharmaceutical intermediates or API to customers under tight time, cost and quality constraints.
• Design safe, robust, and cost effective multi-step chemical processes for the large-scale manufacture (1kg to 300kg) of pharmaceutical intermediates or APIs for pre-clinical studies and catalog products.
• Lead technology transfer to external partners for further scale-up or GMP activities.
• Implement process analytical technologies in the laboratory that facilitate and increase lab productivity and efficiency.
• Provide leadership in the continuous improvement initiatives and the redesign of the laboratories and building extensions.
• Provide technical support in problem solving.
• Supervise associates, mentor colleagues, and conduct performance appraisals.
• Active facilitator in the communications between process chemistry, purchassing, QC, financial and customers.
• Jury member for the annual innovation awards.
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OmegaChem Inc.
- Associate Director
2009 - 2016
Responsible for KiloLab and process development activities: staff supervision, start-up of a new laboratory for the development of large scale processes, creation and training on SOPs, ways of working and safety, etc..
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Wyeth Research, Montreal, Canada
- Chercheur senior - Chef de projets
2007 - 2009
Chemical Process Development
Responsible for route selection activities and material supply for First Tox Dose (500g) and beyond.
Team Leader role for proposal and exploration of potential routes, phase appropriate process development, assessment of safety and scalability, transfer to the pilot plant and production of the clinical API lots.
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Eli Lilly and Company, Mont-Saint-Guibert, Belgium
- Senior Research Scientist
2003 - 2006
Responsible for route selection activities and material supply from First Tox Dose (500g) to Phase II (100kg).
Proposal and exploration of routes, phase appropriate process development, transfer to the pilot plant.
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Eli Lilly and Company, Lafayette, Indiana, USA
- Senior Organic Chemist
2001 - 2003
Chemical Process Development
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Eli Lilly, Irish Branch SA, Dunderrow, Ireland
- Process Chemist
1999 - 2001
Responsible for manufacturing processes: technical and scientific support, co-ordination of raw material and final product supply, tracking of QC activities, optimization of throughput, preparation for FDA inspections.
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ICSN-CNRS, Gif-sur-Yvette - Laboratoires Servier, Courbevoie, France
- Doctorant
1995 - 1998
Synthesis, structural analysis and biological evaluation of cell-cycle selective cytotoxic indolizinoindoles.
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University College Cork, Cork, Ireland - Glaxo Group Research, England
- Research Assistant
1994 - 1995
Total synthesis of a natural product, Murrayaquinone A.
