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Targetome SA
- Chief Scientific Officer
2013 - maintenant
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Targetome
- Chief Scientific Officer
2013 - maintenant
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TecnoScent SA.
- Head Industrial Development
2011 - 2012
* Define, develop and implement standard processes and procedures for production
* Responsible of the production and high throughput screening
* Instrumental in the development of in-house sensory testing
* Identify in collaboration with Business Development new potential markets and Partners ;
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Enlighten Clinical Diagnostics Associates Inc.
- Associate
2011 - 2011
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Integrated Diagnostics
- Consultant
2010 - 2013
Rx and Dx identification and characterization
* Development of antibody/affinity-based diagnostics and therapeutics
* Therapeutics target identification, evaluation/annotation
* Development of functional in vitro and cell based assay for peptide/protein therapeutics characterization
* ;
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ChemCom SA.
- Research Consultant
2010 - 2011
* Evaluation and development of potential new research projects ;
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CHU Sainte Justine
- Research Consultant & Collaborative Investigator
2007 - 2009
Department of Nutrition, Research Centre, CHU Sainte Justine
* Development of antibody-based diagnostics ;
* Development of enzyme activity-based diagnostics assay
* Mentoring of students and post docs (in biochemical, cell and molecular biology techniques) ;
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PerkinElmer
- Project Management Consultant
Villebon sur Yvette
2007 - 2007
PerkinElmer Inc. Montreal, QC, Canada
* Management of Product Development Projects ;
* Feasibility evaluation of internal research projects for development of high throughput screening assays
* Research project consultant (for post doctoral project)
Accomplishments:
* Generation of AlphaLISA kit product information for customers and PerkinElmer Drug Discovery Specialists
* Establishment of a new AlphaLISA Assay Development Guide ;
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HyperOmics Farma, Inc.
- Director R&D
2003 - 2009
* Development of antibody-based diagnostics (design, development, stability assays)
* Protein expression strategy and peptide antigen design
* Proteomics Target Discovery consulting (biomarkers and therapeutics target selection using data generated during analysis, biological properties of potential candidates as well as IP search information)
* Development of new complementary biological tools facilitating the use of chicken antibodies
* Evaluate new collaborations with industry and academics, assess feasibility and business potential of new projects
* Daily management of the generation of polyclonal custom antibodies and the expression of recombinant proteins
Accomplishments:
* High success rate for anti-peptide and anti-protein antibodies
* Collaborations with research groups in Canada, Europe and China ;
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Caprion Pharmaceuticals Inc.
- Senior Scientist
2001 - 2001
* Leader of the subcellular fractionation laboratory - management and coaching of an 8-person team
Accomplishments:
* Development of subcellular fractionation methods for isolation of plasma membrane fractions from cancerous and healthy colon tissue epithelium for subsequent proteomics (mass spectrometry) analysis
* Implicated in laboratory design in collaboration with architects and implementation with foreman during construction of the new facility.
* Implementation of standardized procedures and practices in the laboratory ;
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Caprion Pharmaceuticals Inc.
- Group Leader
2001 - 2002
Caprion Pharmaceuticals Inc. Montreal, QC, Canada
* Protein target identification, evaluation/annotation expert, Oncology Program
* Defining bioinformatics tools for proteomics target discovery
* Platform integration between different departments - Management of a ±20-person team in a matrix environment (between Molecular & Cellular Biology Dept, the Protein Analysis (Mass Spec) Dept, and the BioInformatics & IT Depts)
* Development of internal guidelines and SOPs for R&D laboratories
* Head of animal care committee & BioSafety Officer
Accomplishments:
* Development of the proteomics target discovery platform; defining process flow from the generation of samples (epithelial cell surface proteins) all the way to establishment of bioinformatics tools for interpretation of mass spec data and subsequent protein identification, potential target identification and initial IP landscape evaluation
* Generation of protein target lists (for generation of potential immunotherapeutics); annotated and characterized hundreds of Oncology Protein Targets for marketing to clients/partners ;
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Dr. B Herman
- Exchange Scholar
1989 - 1990
Dept. of Anatomy & Cell Biology, UNC, Chapel Hill, NC, USA
* Research project on Oxidative stress in endothelial cells
Accomplishments:
* Developed a method for purification and culture of liver endothelial cells
* Setting up new methods in the laboratory for culturing primary cells ;
