2014 - maintenant Responsable du service R&D Analytique:
- Developpement de nouvelles méthodes d'Analyses par HPLC ou spéctrométrie IR, UV, MS.
- Validation
- Encadrement de techniciens et cadres
Supervision technique de la Supply Chain du Fondaparinux:
- Gestion des fournisseurs d'intermédiaires de synthèse utilisés, suivis des campagnes (40 étapes de synthèse), résolution des problèmes, amélioration continue et transferts de technologie
- Gestion de la production du Fondaparinux crude, suivis des campagnes chez nos fournisseurs (13 étapes de synthèse GMP), résolution des problèmes et transferts technologiques, amélioration continue
Lipomed AG
- Chercheur en chimie médicinale
2007 - 2014Responsable de la recherche: Synthèse organique et développement de nouvelles molécules (prodrug d'analogues de nucléosides) dans le domaine de l'Oncologie.
University of Basel
- Research and Teaching Assistant
2005 - 2007Research:
Project Leader for c-di-GMP project in the Prof. Giese's group in Basel.
c-di-GMP is a natural compound that has gained more and more attention in the last few years. We have found properties for this molecule that makes it very promising for future medical applications. However, this molecule was very expensive since its synthesis was still rather difficult. A new synthetic approach that allowed gram scale production of c-di-GMP was achieved.
Teaching:
Practical work in Organic Chemistry and General Chemistry for 1st and 2nd year students at the University of Basel
University of Basel
- Post-Doctoral Fellowship
2001 - 2004Development of different organic compounds:
- Synthesis and study of unnatural DNA strands to study the electron transfer into DNA
- New synthesis for c-di-GMP a very important RNA derivative that plays a role in bacterial development
